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Calcium Hydroxyapatite Microsphere Gel

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Product Description

Calcium hydroxyapatite microsphere gel filler, 3 mL (generic for Radiesse)  

  • Calcium hydroxyapatite microsphere gel is FDA-approved for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds and it is also intended for restoration and/or correction of the signs of facial fat loss.
  • Treatment with calcium hydroxyapatite microsphere gel is unique because it utilizes a calcium-based microspheres to provide immediate volume restoration and stimulates the body to produce new collagen. The long-lasting effects of calcium hydroxyapatite microsphere gel provide a duration of effect of 2 years.
  • Calcium hydroxyapatite microsphere gel is FDA-approved for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds.
  • Generic formulation of Radiesse
  • Patients with deep furrows, vertical glabellar lines, and nasolabial folds are very good candidates for facial fillers such as calcium hydroxyapatite microsphere gel. Calcium hydroxyapatite is effective for glabellar frown lines, support of the brows, tear troughs, nasolabial folds, nose, lips, perioral region, marionette lines, oral commisures, and chin.
  • Calcium hydroxyapatite microsphere gel is also a good solution to correct scne scars.
  • Provides natural and long-lasting results for two years. 
  • Sterile, 30% calcium hydroxyapatite microsphere gel, 70% purified carboxymethylcellulose/glycerine gel, 2% lidocaine
  • Look 10 years younger in 10 minutes
  • Made in the Canada


  • Calcium hydroxyapatite microsphere gel may be used for improve­ment of the nasolabial folds, cheeks/mid-face, and marionette lines. 
  • Calcium hydroxyapatite microsphere gel can be used to improve deep folds and lines.
  • Calcium hydroxyapatite microsphere gel is composed of smooth calcium hydroxylapatite (CaHA) microspheres (diameter of 25µm to 45µm) suspended in a sodium carboxymethylcellulose gel carrier. Calcium hydroxyapatite microsphere gel is approximately 30% CaHA and 70% gel carrier by volume.
  • Calcium hydroxyapatite microsphere gel is injected under the skin. Injection of the product provides an immediate and visible correction to the wrinkle. No skin sensitivity testing or reconstitution is required.
  • Over time, fibroblasts appear. The process of neocollagenesis begins, stimulating the gradual growth of the patient’s own collagen. The collagen that forms results in extended correction and increased patient satisfaction. Clinical results have been shown to last for 2 years in many patients.
  • The cosmetic results are immediate, natural and subtle. The correction lasts for 2 years. The CaHA microspheres naturally degrade to calcium and phosphate ions, which are metabolized by the body’s normal processes.

Folds Between the Nose and Mouth Corner

• The nasolabial fold is the groove from the corner of the nose to the outer corner of the mouth. The nasolabial fold deepens with age. Complete flattening or overfilling of the nasolabial fold should be avoided because complete flatting of the nasolabial fold will produce an unnatural appearance.

• Anatomic Considerations

Volume loss of the cheek and droping of the cheek mound can contribute to folding over of the skin.

• Injection Technique

Placement of calcium hydroxyapatite microsphere gel filler in the nasolabial fold region may be performed with the cross­hatching, fanning, linear threading, or serial puncture techniques. The filler should be placed below the skin, and the filler should be massaged into place after injection to reduce lumpiness.


The low area in front of the fold should be filled with calcium hydroxyapatite microsphere gel placed parallel to the fold.

• After Care Instructions

Ice and pressure are helpful to prevent bruising near the nasolabial fold. 

• Risks

Risks of nasolabial fold placement include bruising and bluish color.

• Injection Tips

The nasolabial fold should not be overly flattened because overcorrection and complete flattening of the nasolabial fold will look unnatural.

Calcium hydroxyapatite microsphere gel can be placed  in the nasolabial region under the skin. 


Fig. Techniques to treat the nasolabial fold are shown. (a) Calcium hydroxyapatite microsphere gel filler may be placed along the depth of the fold as well as horizontally to support the filler.


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Other Details

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Product Reviews

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  1. Long lasting 2 years 4 Star Review

    Posted by on Jan 14th 2017

    Good long-term results with minimal lumpiness. Long lasting results are a big positive.

  2. Good and True 5 Star Review

    Posted by on Nov 16th 2015

    May cause some swelling at first. The results are fantastic, I look youthful.

  3. Lasted for 2 years 5 Star Review

    Posted by on Aug 7th 2015

    The duration of the treatment was excellent. I have had smooth cheeks and chin for 2 years. Very nice results. Very comfortable and easy to use.

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